Proteasomes and protein conjugation across domains of life
نویسندگان
چکیده
منابع مشابه
Proteasomes modulate conjugation to the ubiquitin-like protein, ISG15.
ISG15 is a ubiquitin-like protein that is induced by interferon and microbial challenge. Ubiquitin-like proteins are covalently conjugated to cellular proteins and may intersect the ubiquitin-proteasome system via common substrates or reciprocal regulation. To investigate the relationship between ISG15 conjugation and proteasome function, we treated interferon-induced cells with proteasome inhi...
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ژورنال
عنوان ژورنال: Nature Reviews Microbiology
سال: 2011
ISSN: 1740-1526,1740-1534
DOI: 10.1038/nrmicro2696